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The second, Francis Crick, was a 37-year-old British physicist who, according to one of his scientific rivals, looked like "a bookmaker's rout." With booming voices and youthful bravado, the odd duo bragged that they, in the words of Francis Crick -- or at least in the memory of James Watson recalling the words of Francis Crick -- "We have discovered the secret of life." Indeed, they had.

That very morning, the two men worked out the double helix structure of deoxyribonucleic acid, better known to every first-grader as DNA. That scientific feat was actually accomplished in 1869 by Friedrich Miescher, a physiological chemist working in Basel, Switzerland.

Francis Crick's co-discovery of the structure of DNA made it possible for Dr Venter to sequence the human genome 47 years later.

Kindra Crick has designed a DNA sculpture for the auction entitled What Mad Pursuit, which is inspired by her family's contribution to the discovery of the structure of DNA.

Miescher determined that DNA, a nucleic acid found in the cell's nucleus, was comprised of sugar, phosphoric acid, and several nitrogen containing bases.

But for decades, no one quite knew much about its precise function.

In particular multiscale modeling going from explicit quantum description of ground and the excited states, to mesoscale coarse grain simulations passing through an atomistic classical description is fundamental to get a clear comprehension of all these fundamental mechanisms.

Identifying possible selective non covalent modes and interpret their stability. Symmetry and connectivity constraints associated to a given space group allow a certain number of degrees of freedom for a macromolecule to pack intro a three dimensional network of connections.Space groups that allow a greater number of degrees of freedom such as -DNA.Her grandfather, Francis Crick, is best known for his work elucidating the structure of DNA and her grandmother, Odile Crick, is the artist who first drew the iconic image of the double helix molecule.Kindra Crick said, "One strand of the double helix sculpture uses imagery from my grandad's letters and his many chalkboards.




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